Cargando…

A selective CB2R agonist (JWH133) protects against pulmonary fibrosis through inhibiting FAK/ERK/S100A4 signaling pathways

BACKGROUND: The combination of the endocannabinoid system (ECS) and the type 2 cannabinoid receptor (CB2R) can activate various signal pathways, leading to distinct pathophysiological roles. This interaction has gained significant attention in recent research on fibrosis diseases. Focal adhesion kin...

Descripción completa

Detalles Bibliográficos
Autores principales: Wu, Xiao, Chen, Lina, Cheng, Yiju, Zhang, Yuquan, Yang, Wenting, Pan, Lin, Fu, Chenkun, Zhu, Honglan, Zhang, Menglin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10641936/
https://www.ncbi.nlm.nih.gov/pubmed/37957604
http://dx.doi.org/10.1186/s12890-023-02747-3