Exosomal miR-155-5p drives widespread macrophage M1 polarization in hypervirulent Klebsiella pneumoniae-induced acute lung injury via the MSK1/p38-MAPK axis

BACKGROUND: Hypervirulent Klebsiella pneumoniae (hvKp) infection-induced sepsis-associated acute lung injury (ALI) has emerged as a significant clinical challenge. Increasing evidence suggests that activated inflammatory macrophages contribute to tissue damage in sepsis. However, the underlying caus...

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Detalles Bibliográficos
Autores principales: Xu, Yihan, Zhang, Chunying, Cai, Danni, Zhu, Rongping, Cao, Yingping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10641976/
https://www.ncbi.nlm.nih.gov/pubmed/37953267
http://dx.doi.org/10.1186/s11658-023-00505-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10641976/
https://www.ncbi.nlm.nih.gov/pubmed/37953267
http://dx.doi.org/10.1186/s11658-023-00505-1

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