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Circulating cell-free DNA fragmentation is a stepwise and conserved process linked to apoptosis

BACKGROUND: Circulating cell-free DNA (cfDNA) is a pool of short DNA fragments mainly released from apoptotic hematopoietic cells. Nevertheless, the precise physiological process governing the DNA fragmentation and molecular profile of cfDNA remains obscure. To dissect the DNA fragmentation process,...

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Detalles Bibliográficos
Autores principales: Zhu, Dandan, Wang, Haihong, Wu, Wei, Geng, Shuaipeng, Zhong, Guolin, Li, Yunfei, Guo, Han, Long, Guanghui, Ren, Qingqi, Luan, Yi, Duan, Chaohui, Wei, Bing, Ma, Jie, Li, Shiyong, Zhou, Jun, Mao, Mao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10642009/
https://www.ncbi.nlm.nih.gov/pubmed/37953260
http://dx.doi.org/10.1186/s12915-023-01752-6