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Pan-cancer analysis and in vitro validation of the oncogenic and prognostic roles of AURKA in human cancers

BACKGROUND: Aurora kinase A (AURKA) plays a pivotal role in regulating cell mitosis and tumor progression. However, its prognostic significance across diverse cancer types remains relatively unexplored. METHODS: We conducted a comprehensive analysis of AURKA expression in various cancers using data...

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Detalles Bibliográficos
Autores principales: Yang, Chuang, Plum, Patrick Sven, Gockel, Ines, Thieme, René
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10642189/
https://www.ncbi.nlm.nih.gov/pubmed/37965456
http://dx.doi.org/10.3389/fonc.2023.1186101