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The role of cGAS-STING signaling in pulmonary fibrosis and its therapeutic potential

Pulmonary fibrosis is a progressive and ultimately fatal lung disease, exhibiting the excessive production of extracellular matrix and aberrant activation of fibroblast. While Pirfenidone and Nintedanib are FDA-approved drugs that can slow down the progression of pulmonary fibrosis, they are unable...

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Detalles Bibliográficos
Autores principales: Zhang, Jing, Zhang, Lanlan, Chen, Yutian, Fang, Xiaobin, Li, Bo, Mo, Chunheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10642193/
https://www.ncbi.nlm.nih.gov/pubmed/37965345
http://dx.doi.org/10.3389/fimmu.2023.1273248