Complex CDKL5 translational regulation and its potential role in CDKL5 deficiency disorder

CDKL5 is a kinase with relevant functions in correct neuronal development and in the shaping of synapses. A decrease in its expression or activity leads to a severe neurodevelopmental condition known as CDKL5 deficiency disorder (CDD). CDD arises from CDKL5 mutations that lie in the coding region of...

Descripción completa

Detalles Bibliográficos
Autores principales: Ruggiero, Valeria, Fagioli, Claudio, de Pretis, Stefano, Di Carlo, Valerio, Landsberger, Nicoletta, Zacchetti, Daniele
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Cellular Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10642286/
https://www.ncbi.nlm.nih.gov/pubmed/37964795
http://dx.doi.org/10.3389/fncel.2023.1231493

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10642286/
https://www.ncbi.nlm.nih.gov/pubmed/37964795
http://dx.doi.org/10.3389/fncel.2023.1231493

Ejemplares similares