Arginine reprograms metabolism in liver cancer via RBM39

Metabolic reprogramming is a hallmark of cancer. However, mechanisms underlying metabolic reprogramming and how altered metabolism in turn enhances tumorigenicity are poorly understood. Here, we report that arginine levels are elevated in murine and patient hepatocellular carcinoma (HCC), despite re...

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Detalles Bibliográficos
Autores principales: Mossmann, Dirk, Müller, Christoph, Park, Sujin, Ryback, Brendan, Colombi, Marco, Ritter, Nathalie, Weißenberger, Diana, Dazert, Eva, Coto-Llerena, Mairene, Nuciforo, Sandro, Blukacz, Lauriane, Ercan, Caner, Jimenez, Veronica, Piscuoglio, Salvatore, Bosch, Fatima, Terracciano, Luigi M., Sauer, Uwe, Heim, Markus H., Hall, Michael N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10642370/
https://www.ncbi.nlm.nih.gov/pubmed/37804830
http://dx.doi.org/10.1016/j.cell.2023.09.011

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10642370/
https://www.ncbi.nlm.nih.gov/pubmed/37804830
http://dx.doi.org/10.1016/j.cell.2023.09.011

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