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Roles of phosphatidylinositol-3-kinases signaling pathway in inflammation-related cancer: Impact of rs10889677 variant and buparlisib in colitis-associated cancer

BACKGROUND: Phosphatidylinositol-3-kinases (PI3K) is a well-known route in inflammation-related cancer. Recent discovery on PI3K-related genes revealed a potential variant that links ulcerative colitis (UC) and colorectal cancer (CRC) with colitis-associated cancer (CAC). PI3K/AKT pathway has been r...

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Detalles Bibliográficos
Autores principales: Razali, Nurul Nadirah, Raja Ali, Raja Affendi, Muhammad Nawawi, Khairul Najmi, Yahaya, Azyani, Mohd Rathi, Norshafila Diana, Mokhtar, Norfilza Mohd
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Baishideng Publishing Group Inc 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10642440/
https://www.ncbi.nlm.nih.gov/pubmed/37970476
http://dx.doi.org/10.3748/wjg.v29.i40.5543