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Inhibition of Key Glycolytic Enzyme Hexokinase 2 Ameliorates Psoriasiform Inflammation in vitro and in vivo

PURPOSE: Epidermal keratinocytes with an abnormal glucose metabolism have been identified in psoriasis. Hexokinase 2 (HK2) is a crucial enzyme involved in glycolytic metabolic pathways. However, the expression of HK2 and its potential therapeutic effects in psoriasis remains unclear. This study aime...

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Detalles Bibliográficos
Autores principales: Zhuang, Le, Ma, Weiyuan, Jiao, Jing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10642575/
https://www.ncbi.nlm.nih.gov/pubmed/37965102
http://dx.doi.org/10.2147/CCID.S435624