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The absence of surface D-alanylation, localized on lipoteichoic acid, impacts the Clostridioides difficile way of life and antibiotic resistance

INTRODUCTION: The dlt operon encodes proteins responsible for the esterification of positively charged D-alanine on the wall teichoic acids and lipoteichoic acids of Gram-positive bacteria. This structural modification of the bacterial anionic surface in several species has been described to alter t...

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Detalles Bibliográficos
Autores principales: Lacotte, Pierre-Alexandre, Denis-Quanquin, Sandrine, Chatonnat, Eva, Le Bris, Julie, Leparfait, David, Lequeux, Thierry, Martin-Verstraete, Isabelle, Candela, Thomas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10642750/
https://www.ncbi.nlm.nih.gov/pubmed/37965542
http://dx.doi.org/10.3389/fmicb.2023.1267662