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Dose-dependent progression of multiple low-dose streptozotocin-induced diabetes in mice

This study investigated the effects of different multiple low doses of streptozotocin (STZ), namely 35 and 55 mg/kg, on the onset and progression of diabetes in mice. Both doses are commonly used in research, and although both induced a loss of beta cell mass, they had distinct effects on whole gluc...

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Detalles Bibliográficos
Autores principales: Bauer, Brandon M., Bhattacharya, Supriyo, Bloom-Saldana, Elizabeth, Irimia-Dominguez, Jose M., Fueger, Patrick T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Physiological Society 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10642924/
https://www.ncbi.nlm.nih.gov/pubmed/37458461
http://dx.doi.org/10.1152/physiolgenomics.00032.2023