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Dose-dependent progression of multiple low-dose streptozotocin-induced diabetes in mice
This study investigated the effects of different multiple low doses of streptozotocin (STZ), namely 35 and 55 mg/kg, on the onset and progression of diabetes in mice. Both doses are commonly used in research, and although both induced a loss of beta cell mass, they had distinct effects on whole gluc...
Autores principales: | Bauer, Brandon M., Bhattacharya, Supriyo, Bloom-Saldana, Elizabeth, Irimia-Dominguez, Jose M., Fueger, Patrick T. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Physiological Society
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10642924/ https://www.ncbi.nlm.nih.gov/pubmed/37458461 http://dx.doi.org/10.1152/physiolgenomics.00032.2023 |
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