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Identification of a carbohydrate recognition motif of purinergic receptors

As a major class of biomolecules, carbohydrates play indispensable roles in various biological processes. However, it remains largely unknown how carbohydrates directly modulate important drug targets, such as G-protein coupled receptors (GPCRs). Here, we employed P2Y purinoceptor 14 (P2Y14), a drug...

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Detalles Bibliográficos
Autores principales: Zhao, Lifen, Wei, Fangyu, He, Xinheng, Dai, Antao, Yang, Dehua, Jiang, Hualiang, Wen, Liuqing, Cheng, Xi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10642967/
https://www.ncbi.nlm.nih.gov/pubmed/37955640
http://dx.doi.org/10.7554/eLife.85449