Cargando…
Identification of a carbohydrate recognition motif of purinergic receptors
As a major class of biomolecules, carbohydrates play indispensable roles in various biological processes. However, it remains largely unknown how carbohydrates directly modulate important drug targets, such as G-protein coupled receptors (GPCRs). Here, we employed P2Y purinoceptor 14 (P2Y14), a drug...
Autores principales: | Zhao, Lifen, Wei, Fangyu, He, Xinheng, Dai, Antao, Yang, Dehua, Jiang, Hualiang, Wen, Liuqing, Cheng, Xi |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
eLife Sciences Publications, Ltd
2023
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10642967/ https://www.ncbi.nlm.nih.gov/pubmed/37955640 http://dx.doi.org/10.7554/eLife.85449 |
Ejemplares similares
-
Competitive binding of STATs to receptor phospho-Tyr motifs accounts for altered cytokine responses
por: Wilmes, Stephan, et al.
Publicado: (2021) -
Functional interplay between the RK motif and linker segment dictates Oct4–DNA recognition
por: Kong, Xiangqian, et al.
Publicado: (2015) -
Molecular insights into differentiated ligand recognition of the human parathyroid hormone receptor 2
por: Wang, Xi, et al.
Publicado: (2021) -
Learning protein constitutive motifs from sequence data
por: Tubiana, Jérôme, et al.
Publicado: (2019) -
Common activation mechanism of class A GPCRs
por: Zhou, Qingtong, et al.
Publicado: (2019)