Combined Treatment With TGF-β1, Retinoic Acid, and Lactoferrin Robustly Generate Inducible Tregs (iTregs) Against High Affinity Ligand

Forkhead box P3-positive (Foxp3(+))-inducible Tregs (iTregs) are readily generated by TGF-β1 at low TCR signaling intensity. TGF-β1–mediated Foxp3 expression is further enhanced by retinoic acid (RA) and lactoferrin (LF). However, the intensity of TCR signaling required for induction of Foxp3 expres...

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Detalles Bibliográficos
Autores principales: Jang, Young-Saeng, Park, Sun-Hee, Kang, Seung-Goo, Lee, Jung-Shin, Ko, Hyun-Jeong, Kim, Pyeung-Hyeun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Association of Immunologists 2023
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10643331/
https://www.ncbi.nlm.nih.gov/pubmed/37970231
http://dx.doi.org/10.4110/in.2023.23.e37

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10643331/
https://www.ncbi.nlm.nih.gov/pubmed/37970231
http://dx.doi.org/10.4110/in.2023.23.e37

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