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Cytotoxic n-Hexane Fraction of the Egyptian Pteris vittata Functions as Anti-breast Cancer Through Coordinated Actions on Apoptotic and Autophagic Pathways

We investigated the possible anticancer mechanisms of Pteris vittata [PV] n-hexane extract on MCF-7 [breast cancer cell line]. Cultured cell lines were treated with various concentrations of this extract ± Baf-A1 [autophagic inhibitor]. Cells’ viability, apoptotic markers [caspase-7, Bax, and Bcl-2]...

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Detalles Bibliográficos
Autores principales: Mohany, Khalid M., Abdel Shakour, Abo Bakr, Mohamed, Sara Ibrahim, Hanna, Randa Samir, Nassar, Ahmed Y.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10643356/
https://www.ncbi.nlm.nih.gov/pubmed/36951939
http://dx.doi.org/10.1007/s12010-023-04464-3