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Induced alternative splicing an opportunity to study PCSK9 protein isoforms at physiologically relevant concentrations
Splice modulating antisense oligomers (AOs) are increasingly used to modulate RNA processing. While most are investigated for their use as therapeutics, AOs can also be used for basic research. This study examined their use to investigate internally and terminally truncated proprotein convertase sub...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10643364/ https://www.ncbi.nlm.nih.gov/pubmed/37957262 http://dx.doi.org/10.1038/s41598-023-47005-y |