Induced alternative splicing an opportunity to study PCSK9 protein isoforms at physiologically relevant concentrations

Splice modulating antisense oligomers (AOs) are increasingly used to modulate RNA processing. While most are investigated for their use as therapeutics, AOs can also be used for basic research. This study examined their use to investigate internally and terminally truncated proprotein convertase sub...

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Detalles Bibliográficos
Autores principales: Cale, Jessica M., Ham, Kristin A., Li, Dunhui, McIntosh, Craig S., Watts, Gerald F., Wilton, Steve D., Aung-Htut, May T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10643364/
https://www.ncbi.nlm.nih.gov/pubmed/37957262
http://dx.doi.org/10.1038/s41598-023-47005-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10643364/
https://www.ncbi.nlm.nih.gov/pubmed/37957262
http://dx.doi.org/10.1038/s41598-023-47005-y

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