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A low androgen state impairs erectile function by suppressing EPAC1 in rat penile corpus cavernosum

BACKGROUND: Exchange proteins activated by cAMP 1 (EPAC1) can promote vasodilatation by regulating endothelial nitric oxide synthase (eNOS) activity through the phosphoinositide 3-kinase/protein kinase B (PI3K/AKT) pathway and prevent vascular smooth muscle contraction by restraining the ras homolog...

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Detalles Bibliográficos
Autores principales: Lin, Xi, Long, Hao, Liu, Jing, Xiong, Wenju, Jiang, Rui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: AME Publishing Company 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10643387/
https://www.ncbi.nlm.nih.gov/pubmed/37969773
http://dx.doi.org/10.21037/tau-23-314