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Single-molecule FRET unmasks structural subpopulations and crucial molecular events during FUS low-complexity domain phase separation

Biomolecular condensates formed via phase separation of proteins and nucleic acids are thought to be associated with a wide range of cellular functions and dysfunctions. We dissect critical molecular events associated with phase separation of an intrinsically disordered prion-like low-complexity dom...

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Detalles Bibliográficos
Autores principales: Joshi, Ashish, Walimbe, Anuja, Avni, Anamika, Rai, Sandeep K., Arora, Lisha, Sarkar, Snehasis, Mukhopadhyay, Samrat
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10643395/
https://www.ncbi.nlm.nih.gov/pubmed/37957147
http://dx.doi.org/10.1038/s41467-023-43225-y