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Unistrand piRNA clusters are an evolutionarily conserved mechanism to suppress endogenous retroviruses across the Drosophila genus

The PIWI-interacting RNA (piRNA) pathway prevents endogenous genomic parasites, i.e. transposable elements, from damaging the genetic material of animal gonadal cells. Specific regions in the genome, called piRNA clusters, are thought to define each species’ piRNA repertoire and therefore its capaci...

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Detalles Bibliográficos
Autores principales: van Lopik, Jasper, Alizada, Azad, Trapotsi, Maria-Anna, Hannon, Gregory J., Bornelöv, Susanne, Czech Nicholson, Benjamin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10643416/
https://www.ncbi.nlm.nih.gov/pubmed/37957172
http://dx.doi.org/10.1038/s41467-023-42787-1