Inhibition of insulin-regulated aminopeptidase confers neuroprotection in a conscious model of ischemic stroke

Stroke is a leading cause of mortality and morbidity with a paucity of effective pharmacological treatments. We have previously identified insulin-regulated aminopeptidase (IRAP) as a potential target for the development of a new class of drugs for the treatment of stroke, as global deletion of this...

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Detalles Bibliográficos
Autores principales: Telianidis, Jonathon, Hunter, Andrew, Widdop, Robert, Kemp-Harper, Barbara, Pham, Vi, McCarthy, Claudia, Chai, Siew Yeen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10643421/
https://www.ncbi.nlm.nih.gov/pubmed/37957163
http://dx.doi.org/10.1038/s41598-023-46072-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10643421/
https://www.ncbi.nlm.nih.gov/pubmed/37957163
http://dx.doi.org/10.1038/s41598-023-46072-5

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