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Inhibition of insulin-regulated aminopeptidase confers neuroprotection in a conscious model of ischemic stroke
Stroke is a leading cause of mortality and morbidity with a paucity of effective pharmacological treatments. We have previously identified insulin-regulated aminopeptidase (IRAP) as a potential target for the development of a new class of drugs for the treatment of stroke, as global deletion of this...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10643421/ https://www.ncbi.nlm.nih.gov/pubmed/37957163 http://dx.doi.org/10.1038/s41598-023-46072-5 |