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Exosome-targeted delivery of METTL14 regulates NFATc1 m6A methylation levels to correct osteoclast-induced bone resorption

Osteoporosis has a profound influence on public health. First-line bisphosphonates often cause osteonecrosis of the jaw meanwhile inhibiting osteoclasts. Therefore, it is important to develop effective treatments. The results of this study showed that the increased level of NFATc1 m6A methylation ca...

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Detalles Bibliográficos
Autores principales: Yang, Jin-Gang, Sun, Bao, Wang, Zheng, Li, Xing, Gao, Jia-hui, Qian, Jia-jun, Li, Jiang, Wei, Wen-jia, Zhang, Ping, Wang, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10643436/
https://www.ncbi.nlm.nih.gov/pubmed/37957146
http://dx.doi.org/10.1038/s41419-023-06263-4