A transcriptional evaluation of the melanoma and squamous cell carcinoma TIL compartment reveals an unexpected spectrum of exhausted and functional T cells

INTRODUCTION: Significant heterogeneity exists within the tumor-infiltrating CD8 T cell population, and exhausted T cells harbor a subpopulation that may be replicating and may retain signatures of activation, with potential functional consequences in tumor progression. Dysfunctional immunity in the...

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Detalles Bibliográficos
Autores principales: Cameron, Cheryl M., Richardson, Brian, Golden, Jackelyn B., Phoon, Yee Peng, Tamilselvan, Banumathi, Pfannenstiel, Lukas, Thapaliya, Samjhana, Roversi, Gustavo, Gao, Xing-Huang, Zagore, Leah L., Cameron, Mark J., Gastman, Brian R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Oncology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10643547/
https://www.ncbi.nlm.nih.gov/pubmed/38023136
http://dx.doi.org/10.3389/fonc.2023.1200387

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10643547/
https://www.ncbi.nlm.nih.gov/pubmed/38023136
http://dx.doi.org/10.3389/fonc.2023.1200387

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