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Ubc9 regulates the expression of MHC II in dendritic cells to enhance DSS-induced colitis by mediating RBPJ SUMOylation

SUMOylation is an evolutionary conserved regulatory mechanism, in which Ubc9 is the only E2 conjugating enzyme. Previous studies demonstrated that SUMOylation is involved in multiple biological processes, but its role in dendritic cells (DCs) remains to be fully addressed. Herein in this report, we...

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Detalles Bibliográficos
Autores principales: Zhang, Jing, Chen, Longmin, Xu, Qianqian, Zou, Yuan, Sun, Fei, Zhou, Qing, Luo, Xi, Li, Yang, Chen, Cai, Zhang, Shu, Xiong, Fei, Yang, Ping, Liu, Shiwei, Wang, Cong-Yi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10643556/
https://www.ncbi.nlm.nih.gov/pubmed/37957143
http://dx.doi.org/10.1038/s41419-023-06266-1