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Detection and therapeutic implications of homologous recombination repair deficiency in pancreatic cancer: a narrative review
BACKGROUND AND OBJECTIVE: Pancreatic ductal adenocarcinoma (PDAC) remains one of the most lethal cancers. A major recent advance has been the identification of a subset of patients with PDAC who harbor inherited or somatic genetic alterations that result in homologous recombination deficiency (HRD)...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
AME Publishing Company
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10643583/ https://www.ncbi.nlm.nih.gov/pubmed/37969835 http://dx.doi.org/10.21037/jgo-23-85 |