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Detecting continuous structural heterogeneity in single-molecule localization microscopy data

Fusion of multiple chemically identical complexes, so-called particles, in localization microscopy, can improve the signal-to-noise ratio and overcome under-labeling. To this end, structural homogeneity of the data must be assumed. Biological heterogeneity, however, could be present in the data orig...

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Detalles Bibliográficos
Autores principales: Haghparast, Sobhan, Stallinga, Sjoerd, Rieger, Bernd
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10643625/
https://www.ncbi.nlm.nih.gov/pubmed/37957186
http://dx.doi.org/10.1038/s41598-023-46488-z