Cargando…

PPP1R12A is a recycling endosomal phosphatase that facilitates YAP activation

Yes-associated protein (YAP) is a transcriptional coactivator that is essential for the malignancy of various cancers. We have previously shown that YAP activity is positively regulated by phosphatidylserine (PS) in recycling endosomes (REs). However, the mechanism by which YAP is activated by PS in...

Descripción completa

Detalles Bibliográficos
Autores principales: Inoue, Chiaki, Mukai, Kojiro, Matsudaira, Tatsuyuki, Nakayama, Jun, Kono, Nozomu, Aoki, Junken, Arai, Hiroyuki, Uchida, Yasunori, Taguchi, Tomohiko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10643656/
https://www.ncbi.nlm.nih.gov/pubmed/37957190
http://dx.doi.org/10.1038/s41598-023-47138-0