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PPP1R12A is a recycling endosomal phosphatase that facilitates YAP activation
Yes-associated protein (YAP) is a transcriptional coactivator that is essential for the malignancy of various cancers. We have previously shown that YAP activity is positively regulated by phosphatidylserine (PS) in recycling endosomes (REs). However, the mechanism by which YAP is activated by PS in...
Autores principales: | Inoue, Chiaki, Mukai, Kojiro, Matsudaira, Tatsuyuki, Nakayama, Jun, Kono, Nozomu, Aoki, Junken, Arai, Hiroyuki, Uchida, Yasunori, Taguchi, Tomohiko |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10643656/ https://www.ncbi.nlm.nih.gov/pubmed/37957190 http://dx.doi.org/10.1038/s41598-023-47138-0 |
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