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HES1 promotes aerobic glycolysis and cancer progression of colorectal cancer via IGF2BP2-mediated GLUT1 m6A modification

Aerobic glycolysis has been shown to play a key role in tumor cell proliferation and metastasis. However, how it is directly regulated is largely unknown. Here, we found that HES1 expression was significantly higher in CRC tissues than that in adjacent normal tissues. Moreover, high HES1 expression...

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Detalles Bibliográficos
Autores principales: Wang, Jiayu, Zhu, Mengxin, Zhu, Jinghan, Li, Juntao, Zhu, Xingchao, Wang, Kun, Shen, Kanger, Yang, Kexi, Ni, Xiangyu, Liu, Xin, Zhang, Guangbo, Xi, Qinhua, Shi, Tongguo, Chen, Weichang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10643658/
https://www.ncbi.nlm.nih.gov/pubmed/37957183
http://dx.doi.org/10.1038/s41420-023-01707-4