Significance of micro-EGFR T790M mutations on EGFR-tyrosine kinase inhibitor efficacy in non-small cell lung cancer

Small amounts of epidermal growth factor receptor (EGFR) T790M mutation (micro-T790M), which is detected using droplet digital PCR (ddPCR) but not conventional PCR, in formalin-fixed and paraffin-embedded (FFPE) samples have been investigated as a predictive factor for the efficacy of EGFR-tyrosine...

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Detalles Bibliográficos
Autores principales: Masuda, Takeshi, Miura, Satoru, Sato, Yuki, Tachihara, Motoko, Bessho, Akihiro, Nakamura, Atsushi, Miyawaki, Taichi, Yoshimine, Kohei, Mori, Masahide, Shiraishi, Hideaki, Hamai, Kosuke, Haratani, Koji, Maeda, Sumiko, Tabata, Eriko, Kitagawa, Chiyoe, Tanizaki, Junko, Imai, Takumi, Nogami, Shohei, Yamamoto, Nobuyuki, Nakagawa, Kazuhiko, Hattori, Noboru
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10643699/
https://www.ncbi.nlm.nih.gov/pubmed/37957228
http://dx.doi.org/10.1038/s41598-023-45337-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10643699/
https://www.ncbi.nlm.nih.gov/pubmed/37957228
http://dx.doi.org/10.1038/s41598-023-45337-3

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