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GSK3β Inhibition Prevents Macrophage Reprogramming by High-Dose Methotrexate

Methotrexate (MTX) is an antifolate drug used as a chemotherapeutic agent for acute lymphoblastic leukemia, where MTX improves patients' prognosis. Macrophage reprogramming is being increasingly assessed as an antitumor therapeutic strategy. However, and although MTX limits the pathogenic actio...

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Detalles Bibliográficos
Autores principales: Ríos, Israel, López-Navarro, Baltasar, Torres-Torresano, Mónica, Soler Palacios, Blanca, Simón-Fuentes, Miriam, Domínguez-Soto, Ángeles, Muller, Ittai B., Jansen, Gerrit, Corbí, Ángel L., Puig-Kröger, Amaya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: S. Karger AG 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10643894/
https://www.ncbi.nlm.nih.gov/pubmed/36380627
http://dx.doi.org/10.1159/000526622