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GSK3β Inhibition Prevents Macrophage Reprogramming by High-Dose Methotrexate
Methotrexate (MTX) is an antifolate drug used as a chemotherapeutic agent for acute lymphoblastic leukemia, where MTX improves patients' prognosis. Macrophage reprogramming is being increasingly assessed as an antitumor therapeutic strategy. However, and although MTX limits the pathogenic actio...
Autores principales: | Ríos, Israel, López-Navarro, Baltasar, Torres-Torresano, Mónica, Soler Palacios, Blanca, Simón-Fuentes, Miriam, Domínguez-Soto, Ángeles, Muller, Ittai B., Jansen, Gerrit, Corbí, Ángel L., Puig-Kröger, Amaya |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
S. Karger AG
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10643894/ https://www.ncbi.nlm.nih.gov/pubmed/36380627 http://dx.doi.org/10.1159/000526622 |
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