Ex vivo and in vitro Monocyte Responses Do Not Reflect in vivo Immune Responses and Tolerance

Cytokine production by ex vivo (EV)-stimulated leukocytes is commonly used to gauge immune function and frequently proposed to guide immunomodulatory therapy. However, whether EV cytokine production capacity accurately reflects the in vivo (IV) immune status is largely unknown. We investigated relat...

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Detalles Bibliográficos
Autores principales: Jansen, Aron, Bruse, Niklas, Waalders, Nicole, Gerretsen, Jelle, Rijbroek, Daniëlle, Pickkers, Peter, Kox, Matthijs
Formato: Online Artículo Texto
Lenguaje:English
Publicado: S. Karger AG 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10643897/
https://www.ncbi.nlm.nih.gov/pubmed/35940121
http://dx.doi.org/10.1159/000525572

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10643897/
https://www.ncbi.nlm.nih.gov/pubmed/35940121
http://dx.doi.org/10.1159/000525572

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