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Bruton's Tyrosine Kinase in Neutrophils Is Crucial for Host Defense against Klebsiella pneumoniae

Humans with dysfunctional Bruton's tyrosine kinase (Btk) are highly susceptible to bacterial infections. Compelling evidence indicates that Btk is essential for B cell-mediated immunity, whereas its role in myeloid cell-mediated immunity against infections is controversial. In this study, we de...

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Detalles Bibliográficos
Autores principales: Liu, Zhe, De Porto, Alexander P.N.A., De Beer, Regina, Roelofs, Joris J.T.H., De Boer, Onno J., Florquin, Sandrine, Van't Veer, Cornelis, Hendriks, Rudi W., Van der Poll, Tom, De Vos, Alex F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: S. Karger AG 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10643901/
https://www.ncbi.nlm.nih.gov/pubmed/35537415
http://dx.doi.org/10.1159/000524583