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Bruton's Tyrosine Kinase in Neutrophils Is Crucial for Host Defense against Klebsiella pneumoniae
Humans with dysfunctional Bruton's tyrosine kinase (Btk) are highly susceptible to bacterial infections. Compelling evidence indicates that Btk is essential for B cell-mediated immunity, whereas its role in myeloid cell-mediated immunity against infections is controversial. In this study, we de...
Autores principales: | Liu, Zhe, De Porto, Alexander P.N.A., De Beer, Regina, Roelofs, Joris J.T.H., De Boer, Onno J., Florquin, Sandrine, Van't Veer, Cornelis, Hendriks, Rudi W., Van der Poll, Tom, De Vos, Alex F. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
S. Karger AG
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10643901/ https://www.ncbi.nlm.nih.gov/pubmed/35537415 http://dx.doi.org/10.1159/000524583 |
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