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Obesity Exacerbates Lupus Activity in Fc Gamma Receptor IIb Deficient Lupus Mice Partly through Saturated Fatty Acid-Induced Gut Barrier Defect and Systemic Inflammation

The prevalence of obesity is increasing, and the coexistence of obesity and systemic lupus erythematosus (lupus) is possible. A high-fat diet (HFD) was orally administered for 6 months in female 8-week-old Fc gamma receptor IIb deficient (FcgRIIb−/−) lupus or age and gender-matched wild-type (WT) mi...

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Detalles Bibliográficos
Autores principales: Udompornpitak, Kanyarat, Charoensappakit, Awirut, Sae-Khow, Kritsanawan, Bhunyakarnjanarat, Thansita, Dang, Cong Phi, Saisorn, Wilasinee, Visitchanakun, Peerapat, Phuengmaung, Pornpimol, Palaga, Tanapat, Ritprajak, Patcharee, Tungsanga, Somkanya, Leelahavanichkul, Asada
Formato: Online Artículo Texto
Lenguaje:English
Publicado: S. Karger AG 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10643905/
https://www.ncbi.nlm.nih.gov/pubmed/36219976
http://dx.doi.org/10.1159/000526206