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Obesity Exacerbates Lupus Activity in Fc Gamma Receptor IIb Deficient Lupus Mice Partly through Saturated Fatty Acid-Induced Gut Barrier Defect and Systemic Inflammation

The prevalence of obesity is increasing, and the coexistence of obesity and systemic lupus erythematosus (lupus) is possible. A high-fat diet (HFD) was orally administered for 6 months in female 8-week-old Fc gamma receptor IIb deficient (FcgRIIb−/−) lupus or age and gender-matched wild-type (WT) mi...

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Autores principales:	Udompornpitak, Kanyarat, Charoensappakit, Awirut, Sae-Khow, Kritsanawan, Bhunyakarnjanarat, Thansita, Dang, Cong Phi, Saisorn, Wilasinee, Visitchanakun, Peerapat, Phuengmaung, Pornpimol, Palaga, Tanapat, Ritprajak, Patcharee, Tungsanga, Somkanya, Leelahavanichkul, Asada
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	S. Karger AG 2022
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10643905/ https://www.ncbi.nlm.nih.gov/pubmed/36219976 http://dx.doi.org/10.1159/000526206

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