Immature Brain Cortical Neurons Have Low Transcriptional Competence to Activate Antiviral Defences and Control RNA Virus Infections

Virus infections of the central nervous system (CNS) cause important diseases of humans and animals. As in other tissues, innate antiviral responses mediated by type I interferons (IFNs) are crucially important in controlling CNS virus infections. The maturity of neuronal populations is an establish...

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Detalles Bibliográficos
Autores principales: Narayanan, Divya, Moily, Nagaraj, McQuilten, Hayley A., Kedzierska, Katherine, Mackenzie, Jason M., Kedzierski, Lukasz, Fazakerley, John K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: S. Karger AG 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10643910/
https://www.ncbi.nlm.nih.gov/pubmed/35738238
http://dx.doi.org/10.1159/000525291

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10643910/
https://www.ncbi.nlm.nih.gov/pubmed/35738238
http://dx.doi.org/10.1159/000525291

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