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Immature Brain Cortical Neurons Have Low Transcriptional Competence to Activate Antiviral Defences and Control RNA Virus Infections
Virus infections of the central nervous system (CNS) cause important diseases of humans and animals. As in other tissues, innate antiviral responses mediated by type I interferons (IFNs) are crucially important in controlling CNS virus infections. The maturity of neuronal populations is an establish...
Autores principales: | Narayanan, Divya, Moily, Nagaraj, McQuilten, Hayley A., Kedzierska, Katherine, Mackenzie, Jason M., Kedzierski, Lukasz, Fazakerley, John K. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
S. Karger AG
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10643910/ https://www.ncbi.nlm.nih.gov/pubmed/35738238 http://dx.doi.org/10.1159/000525291 |
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