Cargando…

Natural product piperlongumine inhibits proliferation of oral squamous carcinoma cells by inducing ferroptosis and inhibiting intracellular antioxidant capacity

BACKGROUND: As a new form of cell death, ferroptosis has been shown to have inhibitory effects on a variety of tumor cells except oral squamous cell carcinoma (OSCC). There were few investigations on the effects and molecular mechanisms of piperlongumine (PL, a ferroptosis inducer) and CB-839 (a GLS...

Descripción completa

Detalles Bibliográficos
Autores principales: Wang, Zi-Qian, Li, Ya-Qi, Wang, Dong-Yang, Shen, Ying-Qiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: AME Publishing Company 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10643964/
https://www.ncbi.nlm.nih.gov/pubmed/37969394
http://dx.doi.org/10.21037/tcr-22-1494