Ketamine promptly normalizes excess norepinephrine and enhances dopamine neuronal activity in Wistar Kyoto rats

Ketamine acts primarily by blocking the N-methyl-D-aspartate (NMDA) receptor at the phencyclidine site. The rapid antidepressant properties of ketamine were demonstrated in the clinic and several behavioral models of depression in rodents. We hypothesized that the normalization of abnormal activity...

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Detalles Bibliográficos
Autores principales: Daniels, Stephen, El Mansari, Mostafa, Hamoudeh, Rami, Blier, Pierre
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10644068/
https://www.ncbi.nlm.nih.gov/pubmed/38026921
http://dx.doi.org/10.3389/fphar.2023.1276309

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10644068/
https://www.ncbi.nlm.nih.gov/pubmed/38026921
http://dx.doi.org/10.3389/fphar.2023.1276309

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