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Ketamine promptly normalizes excess norepinephrine and enhances dopamine neuronal activity in Wistar Kyoto rats
Ketamine acts primarily by blocking the N-methyl-D-aspartate (NMDA) receptor at the phencyclidine site. The rapid antidepressant properties of ketamine were demonstrated in the clinic and several behavioral models of depression in rodents. We hypothesized that the normalization of abnormal activity...
Autores principales: | Daniels, Stephen, El Mansari, Mostafa, Hamoudeh, Rami, Blier, Pierre |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10644068/ https://www.ncbi.nlm.nih.gov/pubmed/38026921 http://dx.doi.org/10.3389/fphar.2023.1276309 |
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