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Polygenic Risk Score, Environmental Tobacco Smoke, and Risk of Lung Adenocarcinoma in Never-Smoking Women in Taiwan

IMPORTANCE: Estimating absolute risk of lung cancer for never-smoking individuals is important to inform lung cancer screening programs. OBJECTIVES: To integrate data on environmental tobacco smoke (ETS), a known lung cancer risk factor, with a polygenic risk score (PRS) that captures overall geneti...

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Detalles Bibliográficos
Autores principales: Blechter, Batel, Chien, Li-Hsin, Chen, Tzu-Yu, Chang, I-Shou, Choudhury, Parichoy Pal, Hsiao, Chin-Fu, Shu, Xiao-Ou, Wong, Jason Y. Y., Chen, Kuan-Yu, Chang, Gee-Chen, Tsai, Ying-Huang, Su, Wu-Chou, Huang, Ming-Shyan, Chen, Yuh-Min, Chen, Chih-Yi, Hung, Hsiao-Han, Hu, Jia-Wei, Shi, Jianxin, Zheng, Wei, Rositch, Anne F., Chen, Chien-Jen, Chatterjee, Nilanjan, Yang, Pan-Chyr, Rothman, Nathaniel, Hsiung, Chao Agnes, Lan, Qing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Medical Association 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10644212/
https://www.ncbi.nlm.nih.gov/pubmed/37955902
http://dx.doi.org/10.1001/jamanetworkopen.2023.39254