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Protective immunity induced by DNA vaccine containing TgGRA35, TgGRA42, and TgGRA43 against Toxoplasma gondii infection in Kunming mice

BACKGROUND: Toxoplasma gondii can cause congenital infection and abortion in humans and warm-blooded animals. T. gondii dense granule proteins, GRA35, GRA42, and GRA43, play a critical role in the establishment of chronic infection. However, their potential to induce protective immunity against T. g...

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Detalles Bibliográficos
Autores principales: Shi, Youbo, Li, Jianbing, Yang, Weili, Chen, Jia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10644269/
https://www.ncbi.nlm.nih.gov/pubmed/38029261
http://dx.doi.org/10.3389/fcimb.2023.1236130