Electrochemical Synthesis of Unnatural Amino Acids via Anodic Decarboxylation of N-Acetylamino Malonic Acid Derivatives

[Image: see text] Broad application of α,α-disubstituted cyclic amino acid derivatives in medicinal chemistry urges for analogue design with improved pharmacokinetic properties. Herein, we disclose an electrochemical approach toward unnatural THF- and THP-containing amino acid derivatives that relie...

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Detalles Bibliográficos
Autores principales: Koleda, Olesja, Prane, Katrina, Suna, Edgars
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2023
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10644390/
https://www.ncbi.nlm.nih.gov/pubmed/37758233
http://dx.doi.org/10.1021/acs.orglett.3c02687

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10644390/
https://www.ncbi.nlm.nih.gov/pubmed/37758233
http://dx.doi.org/10.1021/acs.orglett.3c02687

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