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ACSM5 inhibits ligamentum flavum hypertrophy by regulating lipid accumulation mediated by FABP4/PPAR signaling pathway

BACKGROUND: Ligamentum flavum (LF) hypertrophy is the main cause of lumbar spinal canal stenosis (LSCS). Previous studies have shown that LF hypertrophy tissue exhibits abnormal lipid accumulation, but the regulatory mechanism remains unclear. The objective of this study was to explore the function...

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Detalles Bibliográficos
Autores principales: Cao, Yanlin, Li, Jianjun, Qiu, Sujun, Ni, Songjia, Duan, Yang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10644428/
https://www.ncbi.nlm.nih.gov/pubmed/37957699
http://dx.doi.org/10.1186/s13062-023-00436-z