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The promiscuous development of an unconventional Qa1b-restricted T cell population

MHC-E restricted CD8 T cells show promise in vaccine settings, but their development and specificity remain poorly understood. Here we focus on a CD8 T cell population reactive to a self-peptide (FL9) bound to mouse MHC-E (Qa-1(b)) that is presented in response to loss of the MHC I processing enzyme...

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Detalles Bibliográficos
Autores principales: Manoharan Valerio, Michael, Arana, Kathya, Guan, Jian, Chan, Shiao Wei, Yang, Xiaokun, Kurd, Nadia, Lee, Angus, Shastri, Nilabh, Coscoy, Laurent, Robey, Ellen A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
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Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10644506/
https://www.ncbi.nlm.nih.gov/pubmed/38022509
http://dx.doi.org/10.3389/fimmu.2023.1250316