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DG-Affinity: predicting antigen–antibody affinity with language models from sequences

BACKGROUND: Antibody-mediated immune responses play a crucial role in the immune defense of human body. The evolution of bioengineering has led the progress of antibody-derived drugs, showing promising efficacy in cancer and autoimmune disease therapy. A critical step of this development process is...

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Detalles Bibliográficos
Autores principales: Yuan, Ye, Chen, Qushuo, Mao, Jun, Li, Guipeng, Pan, Xiaoyong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10644518/
https://www.ncbi.nlm.nih.gov/pubmed/37957563
http://dx.doi.org/10.1186/s12859-023-05562-z